Population migration and the variation of dopamine D4 receptor (DRD4) allele frequencies around the globe

Population level variation in DRD4 alleles is attributable to general bottleneck effects that also acted on non-DRD4 genes (317).

In a sample of 128 other alleles, none of the non-DRD4 alleles showed a consistent pattern of relation with migration.

Test
Test Name	Support	Significance	Coefficient	Tail
`UNKNOWN`	Not Supported	`UNKNOWN`	`UNKNOWN`	`UNKNOWN`

Variables
Variable Name	Variable Type	OCM Term(s)
Migration Distance from Origin	Association	Location
Distribution of non-DRD4 Alleles	Association	Genetics

Main Author	Published Year	Hypothesis	Supported	Variables Tested
Chen, Chuansheng	1999	Population-level variation in DRD4 alleles is a result of the distributions of DRD4 alleles in founder groups (317).	Not Supported	2	Cite Related Hypotheses More By Author
Chen, Chuansheng	1999	Populations which have remained near their origin will show a lower proportion of long alleles of DRD4 than those that migrated further away (312).	Supported	2	Cite Related Hypotheses More By Author
Chen, Chuansheng	1999	Within each region, societies with the lowest percentage of long DRD4 alleles will tend to be sedentary, while societies with the highest percentage of long DRD4 alleles will tend to be nomadic (313-314).	Some support	2	Cite Related Hypotheses More By Author
Gören, Erkan	2016	Fraction of land dedicated to pasture will be positively associated with between-population DRD4 exon III expected heterozygosity (7).	Supported	2	Cite Related Hypotheses More By Author
Gören, Erkan	2016	Migratory distance from East Africa will be positively associated with between-population DRD4 exon III expected heterozygosity (2).	Supported	2	Cite Related Hypotheses More By Author