Population migration and the variation of dopamine D4 receptor (DRD4) allele frequencies around the globe

Evolution and Human Behavior Vol/Iss. 20(5) Elsevier Published In Pages: 309-324
By Chen, Chuansheng, Burton, Michael L., Greenberger, Ellen, Dmitrieva, Julia


Populations which have remained near their origin will show a lower proportion of long alleles of DRD4 than those that migrated further away (312).


This finding was consistent across all six migration routes. The proportion of long alleles increased by 4.3% for every 1,000 miles of macromigration.


Test NameSupportSignificanceCoefficientTail
Multiple regressionSupportedUNKNOWNUNKNOWNUNKNOWN


Variable NameVariable Type OCM Term(s)
Distribution of DRD4 AllelesAssociationGenetics
Distance from OriginAssociationLocation